Mcl1-IN-4

Mcl1-IN-4

• CAS Number: 1580484-04-3
• UNSPSC Description: Mcl1-IN-4 is an inhibitor of Mcl1 with an IC50 of 0.2 μM.
• Target Antigen: Bcl-2 Family
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/Mcl1-IN-4.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=C2C(C=CC=C2)=C(C3=CC(NS(C4=CC(N5CCOCC5)=CC=C4)(=O)=O)=C(C(O)=O)C=C3)C=C1
• Molecular Weight: 502.58
• References & Citations: [1]Petros A, et al. Fragment-based Discovery of Potent Inhibitors of the Anti-Apoptotic MCL-1 Protein. Bioorg Med Chem Lett, 24 (6), 1484-1488.|[2]Petros AM, et al. Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1484-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported