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Mcl1-IN-4

CAT: 0804-HY-111467Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111467Size:1 Each
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Description
Mcl1-IN-4 is an inhibitor of Mcl1 with an IC50 of 0.2 μM.
CAS Number
1580484-04-3
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Mcl1-IN-4.html
Solubility
10 mM in DMSO
Smiles
CC1=C2C(C=CC=C2)=C(C3=CC(NS(C4=CC(N5CCOCC5)=CC=C4)(=O)=O)=C(C(O)=O)C=C3)C=C1
Molecular Formula
C28H26N2O5S
Molecular Weight
502.58
References & Citations
[1]Petros A, et al. Fragment-based Discovery of Potent Inhibitors of the Anti-Apoptotic MCL-1 Protein. Bioorg Med Chem Lett, 24 (6), 1484-1488.|[2]Petros AM, et al. Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. Bioorg Med Chem Lett. 2014 Mar 15;24 (6) :1484-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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