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JNJ-20788560

CAT: 0804-HY-11051-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-11051-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-20788560 is a selective and orally active delta opioid receptor agonist with an affinity of 2.0 nM for DOR (rat brain cortex binding assay) . JNJ-20788560 also is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. JNJ-20788560 can be used for the research of the relief of inflammatory hyperalgesia[1].
CAS Number
825649-28-3
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jnj-20788560.html
Purity
98.05
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C2/C(C3=CC=CC=C3OC2=C1)=C4CC(CC5)NC5C/4)N(CC)CC
Molecular Formula
C25H28N2O2
Molecular Weight
388.50
References & Citations
[1]Codd EE, et al. JNJ-20788560 [9- (8-azabicyclo[3.2.1]oct-3-ylidene) -9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. J Pharmacol Exp Ther. 2009 Apr;329 (1) :241-51.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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