Procaspase-IN-5

• Description:

  Procaspase-IN-5 is a human DNA polymerase λ inhibitor. Procaspase-IN-5 has DNA polymerization function and TdT function with an IC50 value of 5.9 μM and 4.5 μM, respectively. Procaspase-IN-5 can be used for the research of cancer[1].

• UNSPSC:

  12352005

• Target:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/procaspase-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1/C(SC(N1)=S)=C/C(C=C2)=CC([N+]([O-])=O)=C2SC3=C(C=CC=C3)C

• Molecular Formula:

  C17H12N2O3S3

• Molecular Weight:

  388.48

• References & Citations:

  [1]Strittmatter T, et al. Expanding the scope of human DNA polymerase λ and β inhibitors. ACS Chem Biol. 2014 Jan 17;9 (1) :282-90.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1489285-17-7]