TWS119 (TFA)

CAT: 0804-HY-110074Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-110074Size:1 Each
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Description
TWS119 TFA is a specific inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway.
CAS Number
[1507095-58-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Others; Wnt
Type
Reference compound
Related Pathways
Others; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tws119-tfa.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=CC(OC2=C3C(NC(C4=CC=CC(N)=C4)=C3)=NC=N2)=C1.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Molecular Formula
C22H16F6N4O6
Molecular Weight
546.38
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Hochstrasser RM. Two-dimensional spectroscopy at infrared and optical frequencies. Proc Natl Acad Sci U S A. 2007 Sep 4;104 (36) :14190-6.|[2]Hochstrasser RM. Two-dimensional spectroscopy at infrared and optical frequencies. Proc Natl Acad Sci U S A. 2007 Sep 4;104 (36) :14190-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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