TRPM8-IN-1

• Description :

  TRPM8-IN-1 (example 14) is an inhibitor of transient receptor potential melastatin-8 (TRPM8) channels, IC50[1].

• UNSPSC :

  12352005

• Target :

  TRP Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/trpm8-in-1.html

• Purity :

  99.44

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(N1C(C2=CC=C(C(F)(F)F)C=C2)C3=C(C=CC=C3)CC1)NC4=CC=C(F)C=C4

• Molecular Formula :

  C23H18F4N2O

• Molecular Weight :

  414.40

• References & Citations :

  [1]Norman, et al. Preparation of substituted dihydroisoquinoline derivatives for use as TRP-M8 receptor ligands. World Intellectual Property Organization, WO2009073203 A1. 2009-06-11.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  TRPM8

• CAS Number :

  [1159996-20-9]