EMD 495235

CAT: 0804-HY-10777Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-10777Size:1 Each
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Description
EMD 495235 is a potent and orally active coagulation factor Xa inhibitor with an IC50 of 5.5 nM and a Ki of 6.8 nM. EMD 495235 shows anticoagulant activities[1].
CAS Number
[811811-33-3]
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/emd-495235.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C(N[C@H](COC)C(NC2=CC=C(N3C(COCC3)=O)C(C)=C2)=O)=O)S1
Molecular Formula
C20H22ClN3O5S
Molecular Weight
451.92
References & Citations
[1]Werner W K R Mederski, et al. Chlorothiophenecarboxamides as P1 surrogates of inhibitors of blood coagulation factor Xa. Bioorg Med Chem Lett. 2004 Dec 6;14 (23) :5817-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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