EMD 495235

• Description :

  EMD 495235 is a potent and orally active coagulation factor Xa inhibitor with an IC50 of 5.5 nM and a Ki of 6.8 nM. EMD 495235 shows anticoagulant activities[1].

• UNSPSC :

  12352005

• Target :

  Factor Xa

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/emd-495235.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC1=CC=C(C(N[C@H](COC)C(NC2=CC=C(N3C(COCC3)=O)C(C)=C2)=O)=O)S1

• Molecular Formula :

  C20H22ClN3O5S

• Molecular Weight :

  451.92

• References & Citations :

  [1]Werner W K R Mederski, et al. Chlorothiophenecarboxamides as P1 surrogates of inhibitors of blood coagulation factor Xa. Bioorg Med Chem Lett. 2004 Dec 6;14 (23) :5817-22.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [811811-33-3]