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EMD 52297

CAT: 0804-HY-129714Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129714Size:1 Each
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Description
EMD 52297 is a Renin inhibitor, with acute hemodynamic and hormonal effects. EMD 52297 also acts as an ACE inhibitor[1][2].
CAS Number
129049-51-0
UNSPSC
12352005
Target
Renin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/emd-52297.html
Smiles
O=C(NC(CC1=CC=CC=C1)C(NC(CC2=CN=CN2)C(NC(C(CC(NC(C(CC)C)C(NCN3N=NC=N3)=O)=O)O)CC4CCCCC4)=O)=O)OC(C)(C)C
Molecular Formula
C39H59N11O7
Molecular Weight
793.96
References & Citations
[1]Miriam T Rademaker, et al. Hemodynamic, hormonal, and renal effects of (pro) renin receptor blockade in experimental heart failure. Circ Heart Fail. 2012 Sep 1;5 (5) :645-52.|[2]Jürgen Maibaum, et al. Renin inhibitors as novel treatments for cardiovascular disease. Expert Opinion on Therapeutic Patents. Volume 13, 2003 - Issue 5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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