AI-3

• Description :

  AI-3 is a potent ARE (antioxidant response element) activator. AI-3 increases the NQO1 at the transcript levels and protein expression levels. AI-3 has the potential for the research of oxidative stress related diseases[1].

• UNSPSC :

  12352005

• Target :

  Others; Quinone Reductase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ai-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(S(=O)(C)=O)SC(Cl)=C2CC(C)(C1)C

• Molecular Formula :

  C11H13ClO3S2

• Molecular Weight :

  292.80

• References & Citations :

  [1]Wang R, et al. In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway. ACS Chem Biol. 2013 Aug 16;8 (8) :1764-74.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [882288-28-0]