AI-3

• Description:

  AI-3 is a potent ARE (antioxidant response element) activator. AI-3 increases the NQO1 at the transcript levels and protein expression levels. AI-3 has the potential for the research of oxidative stress related diseases[1].

• UNSPSC:

  12352005

• Target:

  Others; Quinone Reductase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ai-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(S(=O)(C)=O)SC(Cl)=C2CC(C)(C1)C

• Molecular Formula:

  C11H13ClO3S2

• Molecular Weight:

  292.80

• References & Citations:

  [1]Wang R, et al. In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway. ACS Chem Biol. 2013 Aug 16;8 (8) :1764-74.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [882288-28-0]