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NS3763

CAT: 0804-HY-107603-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-107603-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NS3763 is a selective and noncompetitive GLUK5 receptor antagonist with an IC50 of 1.6 µM. NS3763 does not show significant antagonistic properties on GLUK6, AMPA or NMDA receptors[1].
CAS Number
70553-45-6
UNSPSC
12352005
Hazard Statement
H315-H319-H335-H410
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ns3763.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(NC(C2=CC=CC=C2)=O)C=C(NC(C3=CC=CC=C3)=O)C(C(O)=O)=C1)O
Molecular Formula
C22H16N2O6
Molecular Weight
404.37
Precautions
P261-P264-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P391-P403+P233-P405-P501
References & Citations
[1]Jeppe K Christensen, et al. In vitro characterization of 5-carboxyl-2,4-di-benzamidobenzoic acid (NS3763), a noncompetitive antagonist of GLUK5 receptors. J Pharmacol Exp Ther. 2004 Jun;309 (3) :1003-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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