ZD-9379

CAT: 0804-HY-106968Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-106968Size:1 Each
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Description
ZD-9379 is a potent, orally active, and brain penetrant full antagonist at the glycine site of the NMDA receptor. ZD-9379 has neuroprotective effect[1][2].
CAS Number
[170142-20-8]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/zd-9379.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C(NN1C3=C(C=C(OC)C=C3)C)=O)NC4=C(C=CC(Cl)=C4)C2=O
Molecular Formula
C19H14ClN3O4
Molecular Weight
383.79
References & Citations
[1]Tatlisumak T, et al. A glycine site antagonist, ZD9379, reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion. Stroke. 1998;29 (1) :190-195.|[2]ZD 9379. Drugs R D. 1999;1 (1) :44-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
NMDA Receptor

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