ZD-9379

• UNSPSC Description:

  ZD-9379 is a potent, orally active, and brain penetrant full antagonist at the glycine site of the NMDA receptor. ZD-9379 has neuroprotective effect[1][2].

• Target Antigen:

  iGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/zd-9379.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(C(NN1C3=C(C=C(OC)C=C3)C)=O)NC4=C(C=CC(Cl)=C4)C2=O

• Molecular Weight:

  383.79

• References & Citations:

  [1]Tatlisumak T, et al. A glycine site antagonist, ZD9379, reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion. Stroke. 1998;29(1):190-195.|[2]ZD 9379. Drugs R D. 1999;1(1):44-45.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1

• CAS Number:

  170142-20-8