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Fluocortin butyl ester

CAT: 0804-HY-106567Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106567Size:1 Each
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Description
Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when it is used topically. Fluocortin butyl ester appears to be an effective well-tolerated topical steroid useful in the research of perennial rhinitis[1].
CAS Number
41767-29-7
UNSPSC
12352211
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fluocortin-butyl-ester.html
Solubility
10 mM in DMSO
Smiles
C[C@]([C@H]1C(C(OCCCC)=O)=O)(C2)[C@](C[C@H]1C)([H])[C@@](C[C@@H]3F)([H])[C@@]([C@H]2O)([H])[C@](C3=CC4=O)(C=C4)C
Molecular Formula
C26H35FO5
Molecular Weight
446.55
References & Citations
[1]Hartley TF, et al. Efficacy and tolerance of fluocortin butyl administered twice daily in adult patients with perennial rhinitis. J Allergy Clin Immunol. 1985;75 (4) :501-507.|[2][2] Kessler HJ et al. Tierexperimentelle Untersuchungen über den Einfluss von Fluocortin-butylester auf den Verlauf generalisierter Infektionen [Experimental studies in animals on the influence of fluocortin butylester on the course of generalized infections (author's transl) ]. Arzneimittelforschung. 1977;27 (11a) :2214-2216.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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