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Protizinic acid

CAT: 0804-HY-106555Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106555Size:1 Each
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Description
Protizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity. Protizinic acid inhibits phospholipase A2 (PLA2) activity, and the IC50 value is 210 μM[1][2].
CAS Number
13799-03-6
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/protizinic-acid.html
Solubility
10 mM in DMSO
Smiles
CN1C2=C(C=CC(C(C)C(O)=O)=C2)SC3=CC(OC)=CC=C13
Molecular Formula
C17H17NO3S
Molecular Weight
315.39
References & Citations
[1]K Suzuki, et al. Effects of protizinic acid on leukokinin generation and its physiological action. Agents Actions. 1984 Jun;14 (5-6) :699-706.|[2]H Ohnishi, et al. Effects of protizinic acid on the prostaglandins system and the production of oxygen radicals. Nihon Yakurigaku Zasshi. 1982 Jun;79 (6) :561-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A

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