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ZP 120C

CAT: 0804-HY-106234Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106234Size:1 Each
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Description
ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3].
CAS Number
383123-18-0
UNSPSC
12352209
Target
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/zp-120c.html
Solubility
10 mM in DMSO
Smiles
O=C([R][Y][Y][R][W]([K])([K])([K])([K])([K])([K])(N)[K])C
Molecular Formula
C85H141N27O15
Molecular Weight
1781.20
References & Citations
[1]Hadrup N, et al. Opioid receptor-like 1 stimulation in the collecting duct induces aquaresis through vasopressin-independent aquaporin-2 downregulation. Am J Physiol Renal Physiol. 2004 Jul;287 (1) :F160-8. |[2]Rizzi A, et al. Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice. Br J Pharmacol. 2002 Oct;137 (3) :369-74. |[3]Simonsen U, et al. ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries. Br J Pharmacol. 2008 Mar;153 (6) :1185-94.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 2
Isoform
NOP Receptor/ORL1