Capsaicin-d3

• Description:

  Capsaicin-d3 is the deuterium labeled Capsaicin. Capsaicin ((E) -Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory and anti-cancer effects[1][2].

• Product Name Alternative:

  (E) -Capsaicin-d3

• UNSPSC:

  12352005

• Hazard Statement:

  H301

• Target:

  Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; TRP Channel

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis; Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

• Field of Research:

  Cancer

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)/C=C/CCCCC(NCC1=CC(OC([2H])([2H])[2H])=C(C=C1)O)=O

• Molecular Formula:

  C18H24D3NO3

• Molecular Weight:

  308.43

• Precautions:

  H301

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Anandakumar P, et al. Capsaicin provokes apoptosis and restricts benzo (a) pyrene induced lung tumorigenesis in Swiss albino mice. Int Immunopharmacol. 2013 Jun 6;17 (2) :254-259.|[3]Shin YH, et al. The Effect of Capsaicin on Salivary Gland Dysfunction. Molecules. 2016 Jun 25;21 (7) .|[4]McNamara FN, et al. Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1) . Br J Pharmacol. 2005 Mar;144 (6) :781-90.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  1217899-52-9