Capsaicin-d7

CAT: 0804-HY-10448S4Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10448S4Size:1 mg
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Description
Capsaicin-d7 is deuterated labeled Capsaicin (HY-10448) . Capsaicin ((E) -Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory and anti-cancer effects[1][2].
Product Name Alternative
(E) -Capsaicin-d7
UNSPSC
12352005
Target
Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; TRP Channel
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
[2H]C(/C=C/CCCCC(NCC1=CC=C(C(OC)=C1)O)=O)(C([2H])([2H])[2H])C([2H])([2H])[2H]
Molecular Formula
C18H20D7NO3
Molecular Weight
312.46
References & Citations
[1]McNamara FN, et al. Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1) . Br J Pharmacol. 2005 Mar;144 (6) :781-90.|[2]Anandakumar P, et al. Capsaicin provokes apoptosis and restricts benzo (a) pyrene induced lung tumorigenesis in Swiss albino mice. Int Immunopharmacol. 2013 Jun 6;17 (2) :254-259.|[3]Shin YH, et al. The Effect of Capsaicin on Salivary Gland Dysfunction. Molecules. 2016 Jun 25;21 (7) .|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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