CP 376395 (hydrochloride)
CAT:
804-HY-103379
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CP 376395 (hydrochloride)
- CAS Number: 1013933-37-3
- UNSPSC Description: CP 376395 hydrochloride is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist[1][2].
- Target Antigen: CRFR
- Type: Reference compound
- Related Pathways: GPCR/G Protein
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Endocrinology; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/cp-376395-hydrochloride.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=C(OC2=NC(C)=CC(NC(CC)CC)=C2C)C(C)=CC(C)=C1.[H]Cl
- Molecular Weight: 362.94
- References & Citations: [1]Chen YL, et al. 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. J Med Chem. 2008 Mar 13;51(5):1385-92.|[2]Giardino WJ, et al. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption. Alcohol Clin Exp Res. 2013 Jul;37(7):1161-70.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported