C-Met-IN-1

CAT: 0804-HY-101031Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-101031Size:1 Each

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Description

C-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity.[1].

CAS Number

2084836-84-8

UNSPSC

12352005

Target

C-Met/HGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/c-met-in-1.html

Solubility

10 mM in DMSO

Smiles

FC1=CC(NC(C2=CN(C3=C(OC)C=CC=C3)C=N2)=O)=CC=C1OC4=CC=NC5=CC(OCCCN6CCN(C)CC6)=C(OC)C=C54

Molecular Formula

C35H37FN6O5

Molecular Weight

640.70

References & Citations

[1]Wang X, et al. Design, synthesis and biological evaluation of novel 4- (2-fluorophenoxy) quinoline derivatives as selective c-Met inhibitors. Bioorg Med Chem. 2017 Feb 1;25 (3) :886-896.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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