DL-AP7

• Description :

  DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1].

• Product Name Alternative :

  2-APH; 2-Amino-7-phosphonoheptanoic acid

• UNSPSC :

  12352211

• Target :

  IGluR

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dl-ap7.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C(N)CCCCCP(O)(O)=O

• Molecular Formula :

  C7H16NO5P

• Molecular Weight :

  225.18

• References & Citations :

  [1]Chiamulera C, et al. Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology (Berl) . 1990;102 (4) :551-552.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  NMDA Receptor

• CAS Number :

  [85797-13-3]