RegisterLogin

JE-2147

CAT: 0804-HY-100212Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100212Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
JE-2147 (AG1776) is a potent dipeptide protease inhibitor with a Ki of 0.33 nM for HIV-1 protease. JE-2147 has effective activities against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro[1][2].
CAS Number
[186538-00-1]
Product Name Alternative
AG1776; KNI-764
UNSPSC
12352005
Target
HIV; HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/je-2147.html
Solubility
10 mM in DMSO
Smiles
CC(C=CC=C1)=C1CNC([C@H]2N(CSC2(C)C)C([C@@H](O)[C@@H](NC(C3=C(C(O)=CC=C3)C)=O)CC4=CC=CC=C4)=O)=O
Molecular Formula
C32H37N3O5S
Molecular Weight
575.72
References & Citations
[1]Yoshimura K, et al. JE-2147: a dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1. Proc Natl Acad Sci U S A. 1999 Jul 20;96 (15) :8675-80.|[2]Mimoto T, et al. Structure-activity relationship of small-sized HIV protease inhibitors containing allophenylnorstatine. J Med Chem. 1999 May 20;42 (10) :1789-802.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-120229-01GGTI-2147
HY-163151JE-133
HY-123608JE-2178
HY-118916-01FTI-2148
HY-119044KW-2149
HY-P9915252141-V11
HY-10007-01NPS-2143
HY-10171-01NPS-2143 (hydrochloride)
HY-118916AFTI-2148 (diTFA)
HY-10007RNPS-2143 (Standard)

Alternative Products

CatalogName
MBS5781862JE-2147
T25450-01GGTI 2147
sc-221669GGTI-2147
BUP00970GGTI 2147 FA
MBS5781863JE-2178
T86762-01JE-133
70R-JR001JE MCP1 antibody
215000-01MCP-1, Recombinant, Mouse (CCL2, JE, Je, Mcp1, Scya2)
QY-E40248PIG JE Elisa Kit
GWB-BF3F76JE/MCP-1, Antibody

Popular Products