CMX-8933

CMX-8933

• CAS Number: 146877-90-9
• UNSPSC Description: CMX-8933 is an octapeptide fragment of the goldfish brain neurotrophic factor ependymin. CMX-8933 increases the enzymatic activity of c-Jun N-terminal kinase (JNK), increases the phosphorylation of JNK and c-Jun proteins, and increases the cellular levels of c-Jun and c-Fos mRNA. CMX-8933 can be used to study the role of ependymin in neuroplasticity, learning, memory formation, and neural regeneration[1].
• Target Antigen: JNK
• Type: Peptides
• Related Pathways: MAPK/ERK Pathway
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/cmx-8933.html
• Purity: 99.82
• Solubility: H2O : 30 mg/mL (ultrasonic;warming)
• Smiles: O=C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N
• Molecular Weight: 1049.22
• References & Citations: [1]Shashoua V E, et al. CMX-8933, a peptide fragment of the glycoprotein ependymin, promotes activation of AP-1 transcription factor in mouse neuroblastoma and rat cortical cell cultures[J]. Neuroscience letters, 2001, 312(2): 103-107.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported