CMX-2043
CAT:
804-HY-119152-02
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CMX-2043
- Alternative Name: GCA-2
- CAS Number: 910627-26-8
- UNSPSC Description: CMX-2043 is a novel analogue of α-Lipoic Acid (HY-N0492). CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model[1][2].
- Target Antigen: Akt; Insulin Receptor; Tyrosinase
- Type: Peptides
- Related Pathways: Metabolic Enzyme/Protease;PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/cmx-2043.html
- Purity: 99.42
- Solubility: DMSO : 20.83 mg/mL (ultrasonic)
- Smiles: C[C@H](NC([C@@H](NC(CCCC[C@H]1SSCC1)=O)CCC(O)=O)=O)C(O)=O
- Molecular Weight: 406.52
- References & Citations: [1]Alan S Lader, et al. CMX-2043 Mechanisms of Action In Vitro. J Cardiovasc Pharmacol. 2016 Sept;68:241-247. |[2]Baguisi A, et al. CMX-2043 Efficacy in a Rat Model of Cardiac Ischemia-Reperfusion Injury. J Cardiovasc Pharmacol Ther. 2016 Nov;21(6):563-569.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
- Clinical Information: Phase 2