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CMX-2043

CAT: 0804-HY-119152-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119152-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CMX-2043 is a novel analogue of α-Lipoic Acid. CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model[1][2].
CAS Number
910627-26-8
Product Name Alternative
GCA-2, (Rac)-GCA
UNSPSC
12352209
Target
Akt; Insulin Receptor; Tyrosinase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cmx-2043.html
Purity
98.80
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
C[C@H](NC([C@@H](NC(CCCC[C@H]1SSCC1)=O)CCC(O)=O)=O)C(O)=O
Molecular Formula
C16H26N2O6S2
Molecular Weight
406.52
References & Citations
[1]Alan S Lader, et al. CMX-2043 Mechanisms of Action In Vitro. J Cardiovasc Pharmacol. 2016 Sept;68:241-247. |[2]Baguisi A, et al. CMX-2043 Efficacy in a Rat Model of Cardiac Ischemia-Reperfusion Injury. J Cardiovasc Pharmacol Ther. 2016 Nov;21 (6) :563-569.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 2

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