5-LOX-IN-2

5-LOX-IN-2

• CAS Number: 179691-97-5
• UNSPSC Description: 5-LOX-IN-2, an inhibitor of 5-lipoxygenase (5-LOX) with an IC50 of 0.33 μM, inhibits 5-LOX in a dose-dependent manner . 5-LOX-IN-2, reduces the cell viability of renal cancer cells and induces apoptosis, can be used for cancer research[1].
• Target Antigen: Lipoxygenase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-lox-in-2.html
• Smiles: O=C(OCCC1=CC=CC=C1)/C=C/C2=CC(O)=CC=C2O
• Molecular Weight: 284.31
• References & Citations: [1]Selka A, et.al. Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. Eur J Med Chem. 2019 Oct 1;179:347-357.
• Shipping Conditions: Room Temperature