Human TSLP R (Luc) HEK293 Reporter Cell
CAT:
716-CHEK-ATF045-2Vials
Size:
2 Vials
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Human TSLP R (Luc) HEK293 Reporter Cell
- Background: TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.
- Description: TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.
- Host: HEK 293
- Origin Species: Human
- Target: IL-7 R alpha & TSLP R
- Tag: Luc
- Applications: Screen for anti-human TSLP or anti-human TSLP R neutralizing antibody
- Format: Liquid
- Shipping Conditions: Dry ice
- Storage Conditions: Frozen in liquid nitrogen