Human TrkA (Luc) HEK293 Reporter Cell

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: Yes

Product Documents

Datasheet

Alternative Products

Cat	Name
HY-P7308-01	TrkA, Human (HEK293)
iCell-0143a	Human Astroblastoma Cells+Luc [U87MG+Luc Cells]
iCell-0100a	Human Hepatocarcinoma Cell+Luc [HEPG2+Luc Cells]
iCell-0125a	Human Glioma Cells+Luc [LN229+Luc Cells]
MBS8533832-05	TrkA
GT15153	TrkA
HY-P7308-02	TrkA, Human (HEK293)
E8ET1608-44	TrkA
FC15012	TrkA
MBS8565283-02	TRKA

Human TrkA (Luc) HEK293 Reporter Cell

CAT:

716-CHEK-ATF093-2Vials

Size:

2 Vials

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Human TrkA (Luc) HEK293 Reporter Cell

Background: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Description: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Host: HEK 293
Origin Species: Human
Target: TrkA
Tag: Luc
Applications: Screen for neutralizing antibodies blocking the stimulation of human NGF protein. Screen for human TrkA small molecule inhibitor
Format: Liquid
Shipping Conditions: Dry ice
Storage Conditions: Frozen in liquid nitrogen

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