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WNT10B Antibody

CAT: 0800-RQ7426Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7426Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protein Wnt-10b (formerly Wnt12[5]) is a protein that in humans is encoded by the WNT10B gene. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
O00744
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids RLPHHSAILKRGFRE from the human protein were used as the immunogen for the WNT10B antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the WNT10B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This WNT10B antibody is available for research use only.
Storage Conditions
After reconstitution, the WNT10B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the WNT10B antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human PC-3 cells with WNT10B antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= WNT10B antibody.

UniProtKB · O00744

Protein Wnt-10b

WN10B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00744
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WNT10B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R7A5, O00747, Q4VAJ4, Q4VAJ5, Q8WZ97
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Developmental protein

Disease

Disease variant

PTM

Disulfide bondGlycoproteinLipoproteinPhosphoprotein

Cellular component

Extracellular matrixSecreted

Technical term

Proteomics identificationReference proteome

Domain

Signal

Biological process

Wnt signaling pathway

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