ROR alpha Antibody / RORA

• Description:

  RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.

• Specifications:

  Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)

• UniProt:

  P35398

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 193-222 from the human protein was used as the immunogen for the ROR alpha antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  IF, WB, FACS

• Purity:

  Antigen affinity purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the ROR alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This ROR alpha antibody is available for research use only.

• Storage Conditions:

  Aliquot the ROR alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the ROR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Location:

  Nuclear

• Image Legend:

  Western blot testing of human brain lysate with ROR alpha antibody. Predicted molecular weight ~59 kDa.