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Esculentic acid

CAT: 0804-HY-N3866-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3866-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Esculentic acid is a pentacyclic triterpenoid that can be extracted from the Chinese herb Phytolacca esculenta[1][2].
CAS Number
103974-74-9
UNSPSC
12352211
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/esculentic-acid.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@]3(C([C@@]4([H])[C@](C(O)=O)(CC[C@@H](C)[C@@H]4C)CC3)=CC[C@]1([H])[C@@]5([C@@]([C@@](C)([C@H](O)[C@H](O)C5)CO)([H])CC2)C)C
Molecular Formula
C30H48O5
Molecular Weight
488.70
References & Citations
[1]Niu X, et al. Esculentic acid, a novel and selective COX-2 inhibitor with anti-inflammatory effect in vivo and in vitro. Eur J Pharmacol. 2014 Oct 5;740:532-8.|[2]Niu X, et al. Protective effects of esculentic acid against endotoxic shock in Kunming mice. Int Immunopharmacol. 2014 Nov;23 (1) :229-35.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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