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PIWL4 rabbit pAb

CAT: 0855-ES14100-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14100-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]) .[supplied by OMIM, Mar 2008]
Description
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al. 2003 [PubMed 12906857]). [supplied by OMIM, Mar 2008],
UniProt
Q7Z3Z4
Swiss Prot
Q7Z3Z4
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human PIWL4 AA range: 108-158
Target
PIWL4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. PIWIL2/MILI is required for nuclear localization (By similarity) . .
Gene ID (Human)
143689

UniProtKB · Q7Z3Z4

Piwi-like protein 4

PIWL4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q7Z3Z4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PIWIL4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DEG5, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

Developmental proteinRNA-binding

Biological process

DifferentiationMeiosisRNA-mediated gene silencingSpermatogenesisTranslation regulation

PTM

Methylation

Technical term

Proteomics identificationReference proteome

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