(S)-(-)-Propranolol (hydrochloride)

(S)-(-)-Propranolol (hydrochloride)

• CAS Number: 4199-10-4
• UNSPSC Description: (S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2].
• Target Antigen: Adrenergic Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/s-minus-propranolol-hydrochloride.html
• Purity: 99.95
• Solubility: DMSO : 50 mg/mL (ultrasonic)|H2O : ≥ 10 mg/mL
• Smiles: O[C@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl
• Molecular Weight: 295.81
• References & Citations: [1]Jillian G Baker , et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144(3):317-22.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Launched