Thalidomide-O-amido-C7-NH2

• UNSPSC Description:

  Thalidomide-O-amido-C7-NH2 is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/thalidomide-o-amido-c7-nh2.html

• Smiles:

  O=C1CCC(C(N1)=O)N2C(C3=C(C(OCC(NCCCCCCCN)=O)=CC=C3)C2=O)=O

• Molecular Weight:

  444.48

• References & Citations:

  [1]Wang S, et, al. Discovery of novel 20S proteasome subunit β5 PROTAC degraders as potential therapeutics for pharyngeal carcinoma and Bortezomib-resistant multiple myeloma. Bioorg Chem. 2024 Sep 3:153:107801.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2716123-52-1