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Zingibroside R1

CAT: 0804-HY-N6924-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6924-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1]. Zingibroside R1 possesses some anti-HIV-1 activity. Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM) [2].
CAS Number
80930-74-1
UNSPSC
12352005
Target
HIV
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/zingibroside-r1.html
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12C([C@@]3([H])[C@](C(O)=O)(CCC(C)(C)C3)CC2)=CC[C@]4([H])[C@@](C)(CC[C@H](O[C@@]5([H])[C@@H]([C@H]([C@H](O)[C@@H](C(O)=O)O5)O)O[C@]6([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)CO)C7(C)C)[C@@]7([H])CC[C@@]14C
Molecular Formula
C42H66O14
Molecular Weight
794.97
References & Citations
[1]Yoshizaki K, et al. Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus) . Chem Pharm Bull (Tokyo) . 2013;61 (3) :344-50. Epub 2012 Dec 28|[2]Hasegawa H, et al. Inhibitory effect of some triterpenoid saponins on glucose transport in tumor cells and its application to in vitro cytotoxic and antiviral activities. Planta Med. 1994 Jun;60 (3) :240-3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV-1

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