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Notoginsenoside R1

CAT: 0804-HY-N0615-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0615-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells[1][2][3].
CAS Number
80418-24-2
Product Name Alternative
Sanchinoside R1; Sanqi glucoside R1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β; Apoptosis
Type
Natural Products
Related Pathways
Apoptosis; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Notoginsenoside-R1.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]4O)([H])[C@@H]4O[C@@](OC[C@@H](O)[C@@H]5O)([H])[C@@H]5O)[C@@]2([H])C3(C)C)[C@]6([C@@]1([H])[C@]([C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@@H](O)[C@@H]7O)O)O[C@@H]7CO)([H])CC6)C
Molecular Formula
C47H80O18
Molecular Weight
933.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Yu Y, et, al. Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways. Sci Rep. 2016 Feb 18;6:21730.|[2]Ma B, et, al. Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation. Int Immunopharmacol. 2014 Sep;22 (1) :151-9.|[3]Sun K, et, al. Protective effects of ginsenoside Rb1, ginsenoside Rg1, and notoginsenoside R1 on lipopolysaccharide-induced microcirculatory disturbance in rat mesentery. Life Sci. 2007 Jul 19;81 (6) :509-18.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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