Phospho-Acetyl Coenzyme A Carboxylase (S79) Recombinant Rabbit Monoclonal Antibody [JE55-54]

• Description:

  Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme (EC 6.4.1.2) that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC is a multi-subunit enzyme in most prokaryotes and in the chloroplasts of most plants and algae, whereas it is a large, multi-domain enzyme in the cytoplasm of most eukaryotes. The most important function of ACC is to provide the malonyl-CoA substrate for the biosynthesis of fatty acids. The activity of ACC can be controlled at the transcriptional level as well as by small molecule modulators and covalent modification. The human genome contains the genes for two different ACCs —ACACA and ACACB.

• Product Name Alternative:

  ACAC antibody ACACA antibody ACACA_HUMAN antibody ACACB antibody ACC alpha antibody ACC antibody ACC beta antibody ACC-alpha antibody ACC1 antibody ACC2 antibody ACCA antibody ACCB antibody Acetyl CoA carboxylase 1 antibody Acetyl CoA carboxylase 2 antibody Acetyl CoA carboxylase alpha antibody Acetyl CoA carboxylase beta antibody Acetyl Coenzyme A carboxylase alpha antibody Acetyl Coenzyme A carboxylase beta antibody Biotin carboxylase antibody COA1 antibody COA2 antibody HACC275 antibody OTTHUMP00000164069 antibody OTTHUMP00000164070 antibody OTTHUMP00000164076 antibody OTTHUMP00000240532 antibody

• Abbreviation:

  ACACA, ACAC, ACC1, ACCA, ACACB, ACC2, ACCB

• Swiss Prot:

  Q13085 Human, O00763 Human, O00763 Mouse, Q5SWU9 Mouse, O70151 Rat, P11497 Rat

• Cellular Locus:

  Mitochondrion.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic phosphopeptide corresponding to residues surrounding Ser79 of human acetyl-CoA carboxylase protein.

• Isotype:

  IgG

• Clone:

  JE55-54

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB

• Positive Control:

  SH-SY5Y treated with 0.5μM Oligomycin for 30 minutes whole cell lysate.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 277 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3