Phospho-Acetyl Coenzyme A Carboxylase (S79) Recombinant Rabbit Monoclonal Antibody [PSH07-13]

• Description:

  Acetyl-CoA carboxylase 1 also known as ACC-alpha or ACCa is an enzyme that in humans is encoded by the ACACA gene. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA.

• Product Name Alternative:

  ACAC antibody ACACA antibody ACACA_HUMAN antibody ACACB antibody ACC alpha antibody ACC antibody ACC beta antibody ACC-alpha antibody ACC1 antibody ACC2 antibody ACCA antibody ACCB antibody Acetyl CoA carboxylase 1 antibody Acetyl CoA carboxylase 2 antibody Acetyl CoA carboxylase alpha antibody Acetyl CoA carboxylase beta antibody Acetyl Coenzyme A carboxylase alpha antibody Acetyl Coenzyme A carboxylase beta antibody Biotin carboxylase antibody COA1 antibody COA2 antibody HACC275 antibody OTTHUMP00000164069 antibody OTTHUMP00000164070 antibody OTTHUMP00000164076 antibody OTTHUMP00000240532 antibody

• Abbreviation:

  Acaca, Acac, Gm738

• Swiss Prot:

  Q13085 Human, Q5SWU9 Mouse, P11497 Rat

• Cellular Locus:

  Cytoplasm, cytosol.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic phospho-peptide corresponding to residues surrounding Ser79 of human Acetyl Coenzyme A Carboxylase aa 51-100.

• Isotype:

  IgG

• Clone:

  PSH07-13

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P

• Positive Control:

  SH-SY5Y cell lysate, SH-SY5Y treated with 200nM Calyculin A and 1μM Okadaic Acid for 1 hour cell lysate, RAW264.7 cell lysate, RAW264.7 treated with 200nM Calyculin A and 1μM Okadaic Acid for 1 hour cell lysate, C6 cell lysate, C6 treated with 100nM Calyculin A for 30 minutes cell lysate, PC-12, mouse liver tissue, rat liver tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:2,000 ;IF-Cell: 1:50 ;IHC-P: 1:200

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 266 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3