CYC-116

CYC-116

• CAS Number: 693228-63-6
• UNSPSC Description: CYC-116 is a potent aurora A and aurora B inhibitor with Kis of 8 and 9 nM, respectively.
• Target Antigen: Aurora Kinase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/CYC-116.html
• Purity: 98.17
• Solubility: DMSO : 15 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)
• Smiles: CC1=C(SC(N)=N1)C2=NC(NC3=CC=C(C=C3)N4CCOCC4)=NC=C2
• Molecular Weight: 368.46
• References & Citations: [1]Wang S, et al. Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors. J Med Chem. 2010 Jun 10;53(11):4367-78.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Phase 1