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GP130-IN-1

CAT: 0804-HY-168072Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168072Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GP130-IN-1 (compound 49) is a potent GP130 inhibitor with significant in vitro antitumor activity and higher selectivity than Bazedoxifene. GP130-IN-1 induces ultrastructural changes in cells, causing cell cycle arrest in the G0/G1 phase in a time-dependent manner and triggering apoptosis and autophagy. GP130-IN-1 can be used in the study of triple-negative breast cancer[1].
CAS Number
2955243-69-1
UNSPSC
12352005
Target
Apoptosis; Autophagy; Interleukin Related
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gp130-in-1.html
Smiles
O=C(N1C(C2=CC=C(O)C=C2)=CC3=C1C=CC(O)=C3)C4=C(F)C(F)=C(F)C(F)=C4F
Molecular Formula
C21H10F5NO3
Molecular Weight
419.30
References & Citations
[1]Wu P, et al. Structurally diverse design and synthesis of novel 2-phenylindole amide derivatives with anti-canine breast cancer activity[J]. Bioorganic Chemistry, 2024: 107788.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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