GP130-IN-1

• Target:

  Autophagy|||Apoptosis|||Interleukin

• Related Pathways:

  Autophagy|||Apoptosis|||Immunology/Inflammation

• Bioactivity:

  GP130-IN-1 (compound 49) is an effective inhibitor of GP130, demonstrating significant in vitro anti-tumor activity and higher selectivity compared to Bazedoxifene. It induces ultrastructural changes in cells, leading to a time-dependent arrest of the cell cycle at the G0/G1 phase, and triggers both apoptosis and autophagy. GP130-IN-1 is useful for research on triple-negative breast cancer.

• Smiles:

  O=C(C=1C(F)=C(F)C(F)=C(F)C1F)N2C3=CC=C(O)C=C3C=C2C=4C=CC(O)=CC4

• Molecular Formula:

  C21H10F5NO3

• Molecular Weight:

  419.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2955243-69-1