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AL1L1 rabbit pAb

CAT: 0855-ES18410-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES18410-01Size:50 µL
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Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Description
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],
UniProt
O75891
Swiss Prot
O75891
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human AL1L1 AA range: 512-562
Target
AL1L1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol .
Gene ID (Human)
10840

UniProtKB · O75891

Cytosolic 10-formyltetrahydrofolate dehydrogenase

AL1L1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75891
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ALDH1L1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
10-FTHFDH, FDH
EC number
1.5.1.6
Processing
—
Secondary accessions
B4DG36, E9PBX3, Q68CS1, Q8TBP8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphopantetheinePhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Ligand

NADP

Biological process

One-carbon metabolism

Molecular function

Oxidoreductase

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