Wu-5
CAT:
804-HY-153886-03
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Wu-5
- CAS Number: 2630378-05-9
- UNSPSC Description: Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD degradation and induce apoptosis[1].
- Target Antigen: AMPK; Apoptosis; FLT3
- Type: Reference compound
- Related Pathways: Apoptosis;Epigenetics;PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/wu-5.html
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(C1=CC=C(C=C1)OC2=C([N+]([O-])=O)C=C(C(OCC)=O)S2)OC
- Molecular Weight: 351.33
- References & Citations: [1]Miao Yu, et al. Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways. Acta Pharmacol Sin. 2021 Apr;42(4):604-612.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported