Iscartrelvir

• Description:

  Iscartrelvir (WU-04) is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. Iscartrelvir has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV) [1].

• Product Name Alternative:

  WU-04

• UNSPSC:

  12352005

• Target:

  SARS-CoV

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Purity:

  99.84

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N[C@H]1CCCC[C@H]1NC2=C([N+]([O-])=O)C=C(Br)C=C2C(NC)=O)C3=CN=CC4=CC=CC=C43

• Molecular Formula:

  C24H24BrN5O4

• Molecular Weight:

  526.38

• References & Citations:

  [1]Wu J, et al. The molecular mechanism of non-covalent inhibitor WU-04 targeting SARS-CoV-2 3CLpro and computational evaluation of its effectiveness against mainstream coronaviruses. Phys Chem Chem Phys. 2023 Sep 13;25 (35) :23555-23567.. .

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2921711-74-0