E3 ligase Ligand 36

CAT: 0804-HY-168243Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-168243Size:1 Each

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Description

E3 ligase Ligand 36 is an E3 ligase Ligand, and can be used for synthesis of PROTACs, such as PROTAC BRM/BRG1 degrader-1.

CAS Number

3031995-12-4

UNSPSC

12352005

Target

E1/E2/E3 Enzyme; Ligands for E3 Ligase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-36.html

Smiles

OC1=NOC([C@@H](C(C)C)C(N2C[C@H](O)C[C@H]2C(N[C@@H](C)C3=CC=C(C4=C(C)N=CS4)C=C3)=O)=O)=C1

Molecular Formula

C25H30N4O5S

Molecular Weight

498.59

References & Citations

[1]tthew Netherton, et al. Compounds and uses thereof. Patent. WO2021207291

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Von Hippel-Lindau (VHL)

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