E3 ligase Ligand 48

CAT: 0931-MF-0112748-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0112748-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
E3 ligase Ligand 48 is the CRBN ligand of PROTACAR Degrader-9. PROTACAR Degrader-9 (Compound c6) functions as a PROTAC degrader targeting the androgen receptor, effectively degrading AR in human dermal papilla cells (HDPC) with a DC50 of 262.38 nM.
Smiles
C1CC(CN(C1)C2=CC=C(C=C2)C(=O)NC3CCC(=O)NC3=O)C=O
Molecular Formula
C18H21N3O4
Molecular Weight
343.377
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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