E3 ligase Ligand 51

CAT: 0804-HY-W245311-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W245311-01Size:25 mg
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Description
E3 ligase Ligand 51 is the ligand for E3 ligase CRBN that can be used for synthesis of PROTAC BTK Degrader-12 (HY-170413) [1].
CAS Number
[2703915-71-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.0
Smiles
O=CC1CCN(C2=CC=C(N(C(N3)=O)CCC3=O)C=C2)CC1
Molecular Formula
C16H19N3O3
Molecular Weight
301.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang H, et al., Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inhibitors with e3 ligase ligand and methods of use. WO2021219070
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

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