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Piperacillin (sodium)

CAT: 0804-HY-B1286-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1286-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam[1][2][3].
CAS Number
59703-84-3
Product Name Alternative
Sodium piperacillin
UNSPSC
12352005
Hazard Statement
H317, H334
Target
Antibiotic; Bacterial; Penicillin-binding protein (PBP)
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Piperacillin-sodium.html
Purity
98.22
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(N3C(C(N(CC)CC3)=O)=O)=O)C4=CC=CC=C4)=O)N1C2=O)O[Na]
Molecular Formula
C23H26N5NaO7S
Molecular Weight
539.54
Precautions
H317, H334
References & Citations
[1]Tan JS, et al. Antipseudomonal penicillins. Med Clin North Am. 1995 Jul;79 (4) :679-93.|[2]Lau WK, et al. Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection. Antimicrob Agents Chemother. 2006 Nov;50 (11) :3556-61.|[3]Fu KP, et al. Piperacillin, a new penicillin active against many bacteria resistant to other penicillins. Antimicrob Agents Chemother. 1978 Mar;13 (3) :358-67.|[4]Fu KP, et al. Piperacillin, a new penicillin active against many bacteria resistant to other penicillins. Antimicrob Agents Chemother. 1978, 13 (3) :358-67.|[5]Bodey GP, et al. Piperacillin: In Vitro Evaluation. Antimicrob Agents Chemother. 1978, 14 (1) :78-87.|[6]Harada Y, et al. In vitro and in vivo activities of piperacillin-tazobactam and meropenem at different inoculum sizes of ESBL-producing Klebsiella pneumoniae. Clin Microbiol Infect. 2014, 20 (11) :O831-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
Biomed Res Int. 2018 Jul 2:2018:3579832.|bioRxiv. 2024 May 10.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Antimicrob Agents Chemother. 2023 Jun 15;67 (6) :e0160322.|Int J Antimicrob Agents. 2025 Jun 9:107551.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|medRxiv. 2025 Mar 13:2025.03.11.25323422.|Microbiol Spectr. 2023 Feb 14;11 (1) :e0303822.|Microbiol Spectr. 2023 Jun 15;11 (3) :e0069223.|Molecules. 2025 Mar 9;30 (6) :1224.|PLoS Pathog. 2024 Dec 31;20 (12) :e1012783.

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