Piperacillin (hydrate)

• Description:

  Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin hydrate is most commonly used in combination with the β-lactamase inhibitor Tazobactam (HY-B1418) [1][2][3].

• Product Name Alternative:

  Pipracil (hydrate)

• UNSPSC:

  12352005

• Hazard Statement:

  H317-H412

• Target:

  Antibiotic; Bacterial; Beta-lactamase; Penicillin-binding protein (PBP)

• Related Pathways:

  Anti-infection

• Field of Research:

  Cancer; Infection

• Smiles:

  O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(N3C(C(N(CC)CC3)=O)=O)=O)C4=CC=CC=C4)=O)N1C2=O)O.O

• Molecular Formula:

  C23H29N5O8S

• Molecular Weight:

  535.57

• Precautions:

  P261-P272-P273-P280-P302+P352-P362+P364-P501

• References & Citations:

  [1]Fu KP, et al. Piperacillin, a new penicillin active against many bacteria resistant to other penicillins. Antimicrob Agents Chemother. 1978, 13 (3) :358-67. |[2]Bodey GP, et al. Piperacillin: In Vitro Evaluation. Antimicrob Agents Chemother. 1978, 14 (1) :78-87. |[3]Harada Y, et al. In vitro and in vivo activities of piperacillin-tazobactam and meropenem at different inoculum sizes of ESBL-producing Klebsiella pneumoniae. Clin Microbiol Infect. 2014, 20 (11) :O831-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 4

• CAS Number:

  [66258-76-2]