Bac7 (1-35)

• Description:

  Bac7 (1-35) is a proline-rich antimicrobial peptide. Bac7 (1-35) efficiently binds to different regions of prokaryote ribosomes, leading to the inhibition of protein synthesis. Bac7 (1-35) demonstrates in vitro activity against P. aeruginosa strains[1].

• UNSPSC:

  12352209

• Target:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/bac7-1-35.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@@H](CCCNC(N)=N)C(N7[C@@H](CCC7)C(N[C@@H](CC(C)C)C(N8[C@@H](CCC8)C(N[C@@H](CC9=CC=CC=C9)C(N%10[C@@H](CCC%10)C(N[C@@H](CCCNC(N)=N)C(N%11[C@@H](CCC%11)C(NCC(N%12[C@@H](CCC%12)C(N[C@@H](CCCNC(N)=N)C(N%13[C@@H](CCC%13)C(N[C@@H]([C@@H](C)CC)C(N%14[C@@H](CCC%14)C(N[C@@H](CCCNC(N)=N)C(N%15[C@@H](CCC%15)C(N[C@@H](CC(C)C)C(N%16[C@@H](CCC%16)C(N[C@@H](CC%17=CC=CC=C%17)C(N%18[C@@H](CCC%18)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

• Molecular Formula:

  C196H322N68O36

• Molecular Weight:

  4207.09

• References & Citations:

  [1]Runti G, et al. The Mechanism of Killing by the Proline-Rich Peptide Bac7 (1-35) against Clinical Strains of Pseudomonas aeruginosa Differs from That against Other Gram-Negative Bacteria. Antimicrob Agents Chemother. 2017 Mar 24;61 (4) :e01660-16.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported