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Schisandrin

CAT: 0804-HY-N0691-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0691-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats[1][2][3].
CAS Number
[7432-28-2]
Product Name Alternative
Schizandrin; Schizandrol; Schizandrol-A
UNSPSC
12352005
Hazard Statement
H302, H400
Target
Autophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Schisandrin.html
Purity
99.97
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O[C@]1(C)[C@@H](C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C(OC)C(OC)=C(OC)C=C3C1
Molecular Formula
C24H32O7
Molecular Weight
432.51
Precautions
H302, H400
References & Citations
[1]Guo LY, et, al. Anti-inflammatory effects of schisandrin isolated from the fruit of Schisandra chinensis Baill. Eur J Pharmacol. 2008 Sep 4;591 (1-3) :293-9.|[2]Egashira N, et, al. Schizandrin reverses memory impairment in rats. Phytother Res. 2008 Jan;22 (1) :49-52.|[3]Min HY, et, al. Antiproliferative effects of dibenzocyclooctadiene lignans isolated from Schisandra chinensis in human cancer cells. Bioorg Med Chem Lett. 2008 Jan 15;18 (2) :523-6.|[4]Zhang ZL, et, al. Schisandrin A reverses doxorubicin-resistant human breast cancer cell line by the inhibition of P65 and Stat3 phosphorylation. Breast Cancer. 2018 Mar;25 (2) :233-242.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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