Schisandrone

CAT: 0804-HY-N2245-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N2245-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Schisandrone, a 4-aryltetralone lignan, is isolated from the dried fruits of Schisandra sphenanthera[1]. Schisandrone is an alpha-hemolysin (Hla) inhibitor that downregulates the transcript levels of hla, agrA and RNAIII. Hla is an integral virulence determinant in Staphylococcus aureus that determines pathogenicity. Schisandrone is a potent inhibitor against MRSA pneumonia[2].
CAS Number
[98619-25-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
CD74
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/schisandrone.html
Purity
99.85
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1[C@@H](C)[C@@H](C)[C@H](C2=CC=C(OC)C(OC)=C2)C3=C1C=C(O)C(OC)=C3
Molecular Formula
C21H24O5
Molecular Weight
356.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lian-niang, L., et al. Schisandrone, a New 4-Aryltetralone Lignan fromSchisandra sphenanthera. Planta Medica, 1985, 51 (03), 217–219.|[2]Qi Y, et al. An inhibitory effect of schisandrone on -hemolysin expression to combat methicillin-resistant staphylococcus aureus infections. World J Microbiol Biotechnol. 2022 Nov 8;39 (1) :3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N0693-01Schisandrin A
HY-N0691-01Schisandrin
HY-N0089-01Schisandrin B
HY-118129Schisandronic acid
HY-N0690-01Schisandrin C
HY-N0693R-01Schisandrin A (Standard)
HY-N2267-01(+) -Schisandrin B
HY-N0692-01Schisandrol B
HY-N0691RSchisandrin (Standard)
HY-N9233Schisandrin C epoxide

Alternative Products

CatalogName
BUP20031-01Schisandrone
371947Schisandrone discontinued

Popular Products