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Docosanoic acid-d4

CAT: 0804-HY-W013049SSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W013049SSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Docosanoic acid-d4 (Behenic acid-4) is deuterium labeled Docosanoic acid. Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans[1][2][3].
CAS Number
1208430-53-8
Product Name Alternative
Behenic acid-d4
UNSPSC
12352211
Target
DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Smiles
OC(CC([2H])([2H])CC([2H])([2H])CCCCCCCCCCCCCCCCC)=O
Molecular Formula
C22H40D4O2
Molecular Weight
344.61
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Cater NB, et al. Behenic acid is a cholesterol-raising saturated fatty acid in humans. Am J Clin Nutr. 2001 Jan;73 (1) :41-4.|[3]Moreira DK, et al. Evaluation of structured lipids with behenic acid in the prevention of obesity. Food Res Int. 2017 May;95:52-58. |[4]Iijima H, et al. The inhibitory action of long-chain fatty acids on the DNA binding activity of p53. Lipids. 2006 Jun;41 (6) :521-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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