Thalidomide-NH-C4-amide-C3-Br

Thalidomide-NH-C4-amide-C3-Br

• UNSPSC Description: Thalidomide-NH-C4-amide-C3-Br is a conjugate of the E3 ligase ligand Thalidomide with a linker and can be used in the synthesis of PROTAC TBL1X degrader-1 (HY-168190)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-nh-c4-amide-c3-br.html
• Smiles: BrCCCNC(CCCCNC1=C(C(N(C2C(NC(CC2)=O)=O)C3=O)=O)C3=CC=C1)=O
• Molecular Weight: 493.35
• References & Citations: [1]Yang R, et al. Design, Synthesis, and Biological Evaluation of Selective TBL1X Degraders. ACS Med Chem Lett. 2024 Oct 1;15(10):1699-1707.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported